Humulus japonicus (currently treated as Humulus scandens): Published Chromosome Numbers

In Humulus japonicus (= Humulus scandens), several chromosome numbers have been reported in the literature, which has led to recurring confusion. However, some values are well established and consistently documented.

✅ Confirmed & Well-Documented Chromosome Numbers

1️⃣ 2n = 16 (♀, XX)

Repeatedly confirmed

Female plants

Standard XX sex chromosome system

Considered the reference value in many floristic and cytological works

2️⃣ 2n = 17 (♂, XY₁Y₂)

Documented in multiple cytogenetic studies

Male plants

Complex sex chromosome system: XY₁Y₂

The additional Y chromosome explains the odd chromosome number

👉 This is one of the most remarkable features:

H. japonicus exhibits a multiple sex chromosome system (XY₁Y₂), unlike Humulus lupulus and Cannabis sativa, which possess a simpler XY system.

3️⃣ Additional Reported Numbers

Further chromosome counts have been described:

2n = 18

2n = 19 (rare; often associated with unstable lines)

2n = 20 (occasionally reported)

>20 (experimental or induced polyploid lines)

These higher numbers are generally linked to:

Aneuploid populations

Experimental cytogenetic work

Rare or unstable lineages

📊 Summary Table

Sex

Chromosome Number

System

Female

2n = 16

XX

Male

2n = 17

XY₁Y₂

Variable

18–20+

Aneuploid / Polyploid

Why “Humulus japonicus” is not the same as Humulus japonicus

Two annual hops – two completely different biological lineages

In modern botany, Humulus japonicus and Humulus scandens are usually treated as the same species.

However, practical trials, morphology, and cytogenetics suggest a different picture.

🌱 Historically, at least two distinct annual Humulus lineages existed

🔹 Line A: the XX/XY lineage (2n = 20)

classic XX/XY sex system

chromosome number 2n = 20

graft-compatible with Cannabis sativa

shows signs of hybridization potential

morphology:

shorter, rounded cotyledons

rounder leaf shape

more compact growth habit

functionally closer to Cannabis

🔹 Line B: the XY1Y2 lineage (2n = 16/17)

complex multiple-Y sex chromosome system

2n = 16 (♀) / 17 (♂)

not graft-compatible with Cannabis

no signs of hybridization

morphology:

very long, narrow cotyledons

strongly segmented, “cannabis-like” leaves

aggressively climbing growth habit

functionally closer to Humulus lupulus

📊 Short comparison of the two annual hops

Trait | XX/XY lineage | XY1Y2 lineage

Chromosomes | 2n = 20 | 2n = 16 / 17

Sex system | XX / XY | XX / XY1Y2

Cotyledons | short, rounded | long, narrow

Basic leaf form | rounded | narrow, strongly lobed

Growth habit | compact | strongly climbing

Grafting onto Cannabis | ✅ yes | ❌ no

Hybridization signs | ✅ yes | ❌ no

Functional proximity | Cannabis | Hop

🧠 Why this matters

These differences are not minor variations — they involve:

chromosome structure

sex determination

developmental biology

functional compatibility

➡️ These are classic species-level boundaries.

The current taxonomic unification is based on simplification —

not on functional biology.

🌿 Conclusion

There were (and are) two biologically distinct annual hops

that were historically grouped under one name.

Anyone working with grafting, hybridization, or breeding notices the difference immediately.